Thermo Fisher Scientific Cholera Toxin beta Monoclonal Antibody (3D11)
콜레라 독소 베타 서브유닛을 인식하는 단일클론 항체로 ELISA 등 연구용에 적합. 마우스 IgG2b 형식이며 Protein A로 정제됨. 액상 형태로 4°C 보관. Vibrio cholerae 유래 콜레라 독소 연구에 활용 가능.
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Thermo Fisher Scientific Cholera Toxin beta Monoclonal Antibody (3D11)
Applications
- ELISA
Tested Dilution: 1:1,000,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D11 |
| Immunogen | Purified beta subunit of cholera toxin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_558404 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Cholera toxin (CTX, Ctx, or CT) is a protein complex secreted by Vibrio cholerae, the causative agent of cholera infection.
The alpha subunit contains two chains (A1 and A2) linked by a disulfide bridge and activates adenylate cyclase in intestinal mucosa cells, increasing intracellular cAMP levels.
The beta subunit binds to the GM1-ganglioside receptor, initiating toxin action by facilitating uptake and delivery of the alpha subunit into cells.
The holotoxin consists of a pentameric ring of beta subunits surrounding the alpha subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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