Thermo Fisher Scientific Mouse IgG2b Chimeric Recombinant Isotype Control (MOPC-21)
Recombinant mouse IgG2b isotype control (MOPC-21) for use as a negative control in immunoassays. Produced in HEK293 cells and purified via Protein A. Supplied as a 1 mg/mL liquid in PBS with 0.02% ProClin 300. Suitable for various research applications.
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Applications
- Functional Assay (Functional): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Isotype Control |
| Clone | MOPC-21 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
An antibody of unknown specificity that may be used as a negative control.
Target Information
Mouse IgG2b is a subtype of immunoglobulin G antibody produced by B cells in response to an antigen. It is the third most abundant IgG subtype in serum and plays a crucial role in the adaptive immune response.
It consists of two heavy and two light chains and is involved in:
- Opsonization
- Complement activation
- Antibody-dependent cell-mediated cytotoxicity (ADCC)
- Regulation of immune responses, including T cell activation and B cell inhibition
Mouse IgG2b is widely used in research and diagnostic applications such as ELISA, Western blotting, and immunohistochemistry, as well as in therapeutic research including immunotherapy and vaccine development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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