Thermo Fisher Scientific Mouse IgG3 Chimeric Recombinant Isotype Control (MOPC-21)

Applications

Tested Dilution

Functional Assay (Functional)

Assay-dependent

Product Specifications

Host/Isotype

Mouse / IgG3, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Isotype Control

Clone

MOPC-21

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

An antibody of unknown specificity that maybe used as a negative control.

Target Information

Mouse IgG3 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen. It is the least abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response. Mouse IgG3 is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity. It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation. Mouse IgG3 is less commonly used in research and diagnostic applications compared to other IgG subtypes, but it is still used in some applications such as ELISA and immunohistochemistry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.