Thermo Fisher Scientific PRMT6 Polyclonal Antibody
인간 및 마우스 반응성 PRMT6 폴리클로날 항체로, WB 및 In vitro assay에 사용 가능. 합성 펩타이드(aa 23-43)를 면역원으로 제작. 비결합형 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관. 연구용으로만 사용.
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- PA141091
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Thermo Fisher Scientific PRMT6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| In vitro Assay (IV) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 23–43 (CEEDGAEREAALERPRRTKRER) of human PRMT6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | PBS/whole serum with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2253074 |
Product Specific Information
Suggested positive control: HeLa or RAW cells.
Target Information
Protein arginine N-methyltransferase 6 (PRMT6) is a type I PRMT enzyme that forms omega-N monomethylarginine and asymmetric dimethylarginine derivatives on glycine- and arginine-rich substrates.
Acts as a transcriptional coactivator for steroid hormone receptors including ESR1, ESR2, PGR, and NR3C1.
Promotes fasting-induced transcriptional activation of the gluconeogenic program via methylation of CRTC2.
May contribute to innate immunity against HIV-1 by methylating and impairing viral proteins such as Tat, Rev, and Nucleocapsid protein p7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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