Thermo Fisher Scientific Sec23IP/MSTP053 Polyclonal Antibody
Rabbit Polyclonal antibody against Human Sec23-Interacting Protein (SEC23IP). Suitable for WB, IHC, IHC-P, and IP. Recommended dilutions 1:100–1:10,000. Liquid form, 0.20 mg/mL, stored at 4°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,500–1:10,000 | |
| Immunohistochemistry (IHC) | 1:100–1:500 | |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 350–400 of Human Sec23-Interacting Protein (SEC23IP) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC on FFPE tissue sections, epitope retrieval with Tris-EDTA (pH 9.0) is recommended
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
SEC23IP is involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The encoded protein interacts with a mouse protein similar to yeast Sec23p, a key COPII component. It shows similarity to phospholipid-modifying proteins, particularly phosphatidic acid-preferring phospholipase A1. Overexpression can cause disorganization of the ER-Golgi intermediate compartment and Golgi apparatus, indicating a role in the early secretory pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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