Thermo Fisher Scientific Sec23IP/MSTP053 Polyclonal Antibody
SEC23IP 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP에 적합. 4°C에서 보관하며, 액상 형태로 제공. 단백질 수송 연구 및 ER-Golgi 경로 분석에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,500–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunoprecipitation (IP) | 1–4 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 950 and C-terminus of human SEC23IP (UniProt ID: Q9Y6Y8-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with Tris-EDTA (pH 9.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
SEC23IP is involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene interacts with a mouse protein similar to yeast Sec23p, an essential component of COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid-preferring phospholipase A1. Overexpression of SEC23IP causes disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, suggesting its role in the early secretory pathway.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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