Thermo Fisher Scientific Phospho-EIF4G1 (Ser1185) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human EIF4G1(Accession Q04637), corresponding to amino acid residues around phosphorylated Ser1185. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:eIF4G,uniProtId:Q04637-1,ncbiNodeId:9606,antigenRange:1185,antigenLength:1599,antigenImageFileName:PA5-105615_eIF4G_Q04637-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105615_eIF4G_Q04637-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2817043

Product Specific Information

Antibody detects endogenous levels of eIF4G1 only when phosphorylated at Ser1185.

Target Information

The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5`-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.