Thermo Fisher Scientific TRPV4 Polyclonal Antibody
TRPV4 단백질을 인식하는 Rabbit Polyclonal Antibody로서 WB 및 IHC에 사용 가능. Mouse와 Rat 반응성 확인. 합성 펩타이드 항원을 기반으로 제작되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TRPV4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 100–150 of mouse TRPV4 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity of this antibody: TRPV4.
Target Information
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel activated in response to systemic osmotic pressure. It is a non-selective calcium-permeant cation channel involved in osmotic sensitivity and mechanosensitivity.
TRPV4 belongs to the OSM9-like transient receptor potential channel (OTRPC) subfamily in the TRP superfamily of ion channels. Mutations in TRPV4 are associated with spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC.
Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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