Thermo Fisher Scientific TRPC3 Polyclonal Antibody
TRPC3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), IHC(F)에 사용 가능. 마우스, 랫드, 영장류 반응성. 합성 펩타이드 면역원 사용. 동결건조 형태로 제공되며, 4°C 또는 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:500 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Non-human primate, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse TRPC3 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPC3.
Target Information
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the canonical TRP (TRPC) family.
The seven members of this family share activation through PLC-coupled receptors and are suggested to be components of receptor-regulated cation channels in different cell types.
Members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a mechanism of activation by PLC-coupled receptors.
TRPC3 encodes a Ca²⁺-permeant channel that is agonist-activated but not store-operated or directly receptor-activated.
TRPC3 physically interacts with TRPC6 and TRPC7 to form functional tetrameric channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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