Thermo Fisher Scientific GTF2H3 Monoclonal Antibody (OTI6E12), TrueMAB
GTF2H3 단백질을 인식하는 단클론 항체로 Western blot에 적합. Human, Mouse, Rat에서 반응하며, IgG1 아이소타입. 동결건조 형태로 제공되며, PBS 버퍼에 트레할로스 포함. 연구용으로 HIV-1 Tat 관련 전사 복합체 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–241 of human GTF2H3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
GTF2H3 interacts with HIV-1 Tat as part of the HIV-1 transcription pre-initiation complex but is released from the elongation complex containing P-TEFb. It synergizes with HIV-1 Tat to promote transcription elongation from the HIV-1 LTR promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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