Thermo Fisher Scientific APRIL Polyclonal Antibody
Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능한 Rabbit Polyclonal APRIL 항체. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원으로 제작. PBS/glycerol 버퍼에 보관하며 -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TNFSF13 (Accession O75888), corresponding to amino acid residues Y163–S213 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903007 |
Product Specific Information
Antibody detects endogenous levels of total APRIL/TNFSF13.
Target Information
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in this family, APRIL (A Proliferation-Inducing Ligand), also known as TALL2 or TRDL1a, has been identified in human and mouse. Two receptors for APRIL, TACI and BCMA, have been characterized. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death. APRIL and its related ligand BlyS, along with their receptors BCMA and TACI, are implicated in autoimmune diseases and cancer.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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