Thermo Fisher Scientific MSC Polyclonal Antibody
MSC 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot, IHC, ICC/IF에 적합합니다. 인간 및 랫트 시료에 반응하며, Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Applications 및 권장 희석 배수
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MSC (Accession O60682), corresponding to amino acid residues D147–A197 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903006 |
Product Specific Information
This antibody detects endogenous levels of total Musculin.
Target Information
MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many muscle-specific terminal differentiation genes.
MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to repress MyoD activity, resulting in delayed expression of muscle-specific genes.
Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is downregulated during myogenesis and at the onset of terminal differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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