Thermo Fisher Scientific MICA Monoclonal Antibody (6)
인간 MICA 단백질에 특이적인 마우스 단클론 항체. ELISA에 적합하며 비보존제 상태로 제공. 오염 방지를 위해 sodium azide 첨가 권장. 종양 관련 MICA/NKG2D 연구에 활용 가능.
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Applications
ELISA
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6 |
| Immunogen | Recombinant Human MICA protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at −20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2786369 |
Product Specific Information
- This product is preservative free.
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human MICA.
Target Information
Major histocompatibility complex (MHC) class I proteins are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells.
A related family, termed the MHC class I chain-related (MIC) proteins, are recognized by NKG2D—a receptor on NK and T cells—and promote anti-tumor activity.
MICA, a member of the MIC family, is widely expressed on many tumors, and the MICA/NKG2D interaction is thought to stimulate anti-tumor reactivity by T lymphocytes.
Both MICA and MICB mRNA are widely expressed in normal tissues, with MICA being present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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