Thermo Fisher Scientific MEP1B Monoclonal Antibody (09)
Human MEP1B 단백질을 인식하는 Mouse monoclonal antibody로, ELISA에 최적화됨. 보존제 무첨가로 순도 높으며, 단기 4°C, 장기 -20°C 보관 권장. Protein A로 정제된 액상 형태로 제공.
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Applications
ELISA
- Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 09 |
| Immunogen | Recombinant Human MEP1B/Meprin beta Protein (Met1–Thr652) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786365 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human MEP1B/Meprin beta.
Target Information
Meprins are multidomain zinc metalloproteases highly expressed in mammalian kidney and intestinal brush border membranes, leukocytes, and certain cancer cells. They hydrolyze various peptide and protein substrates and are implicated in cancer and intestinal inflammation.
Mature meprins are oligomers of evolutionarily related alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas oligomers containing the beta subunit are plasma membrane-bound.
This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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