Thermo Fisher Scientific MICB Recombinant Rabbit Monoclonal Antibody (103)

Applications

ELISA (ELISA)

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened for optimal performance.
Advantages include:

• Improved specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the rabbit immune repertoire

This antibody specifically recognizes Human MICB/MIC-B.

Target Information

MICB encodes a highly polymorphic MHC (HLA) class I chain-related gene B. The protein is expressed on the cell surface and functions as a stress-induced antigen recognized by intestinal epithelial γδ T cells.
MICB is also recognized by NK cells and T cells expressing the NKG2D receptor. The NKG2D–MICB interaction triggers cytolytic activity of T cells and NK cells against epithelial tumor cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.