Thermo Fisher Scientific Fibrinogen Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:10,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500

-

ELISA (ELISA)

1:20,000-1:100,000

-

Immunoprecipitation (IP)

1:2,000-1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Fibrinogen [Human Plasma] if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Fibrinogen,uniProtId:P02671-1,ncbiNodeId:9606,antigenRange:1-866,antigenLength:866,antigenImageFileName:100-101-240_Fibrinogen_P02671-1_Goat.svg,antigenImageFileNamePDP:100-101-240_Fibrinogen_P02671-1_Goat_PDP.jpeg,sortOrder:1},{targetFamily:Fibrinogen,uniProtId:P02675-1,ncbiNodeId:9606,antigenRange:1-491,antigenLength:491,antigenImageFileName:100-101-240_Fibrinogen_P02675-1_Goat.svg,antigenImageFileNamePDP:100-101-240_Fibrinogen_P02675-1_Goat_PDP.jpeg,sortOrder:2},{targetFamily:Fibrinogen,uniProtId:P02679-1,ncbiNodeId:9606,antigenRange:1-453,antigenLength:453,antigenImageFileName:100-101-240_Fibrinogen_P02679-1_Goat.svg,antigenImageFileNamePDP:100-101-240_Fibrinogen_P02679-1_Goat_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

90 mg/mL

Storage buffer

0.02M potassium phosphate/whole serum, pH 7.2, with 0.15M NaCl

Contains

0.01% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-goat serum, purified and partially purified Fibrinogen [Human Plasma]. Cross reactivity against Fibrinogen from other sources is unknown.

Target Information

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.