Thermo Fisher Scientific Fibrinogen Polyclonal Antibody
인체 Fibrinogen을 인식하는 염소 유래 폴리클로날 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 적합. 비결합형 형태로 제공되며, 고농도(90 mg/mL) 동결건조 제품. 4°C 단기 보관, -20°C 장기 보관 권장.
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Thermo Fisher Scientific Fibrinogen Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC(P)) | 1:500 |
| ELISA | 1:20,000–1:100,000 |
| Immunoprecipitation (IP) | 1:2,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fibrinogen [Human Plasma] |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 90 mg/mL |
| Storage Buffer | 0.02M potassium phosphate/whole serum, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at 4°C prior to restoration.
- For extended storage, aliquot contents and freeze at -20°C or below.
- Avoid cycles of freezing and thawing.
- Centrifuge if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-goat serum, purified and partially purified Fibrinogen [Human Plasma].
Cross-reactivity against Fibrinogen from other sources is unknown.
Target Information
Fibrinogen, the precursor of fibrin, is the coagulable protein in blood plasma. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the main component of blood clots.
Fibrinogen consists of a dimer of three pairs of non-identical chains (FGA, FGB, FGG) cross-linked by disulfide bonds in their N-terminal segments.
The molecule has two terminal D domains and one central E domain, which separate upon degradation by plasmin.
Mutations in this gene can lead to disorders such as dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: Fibrinogen_P02671-1_Goat.svg, Fibrinogen_P02675-1_Goat.svg, Fibrinogen_P02679-1_Goat.svg)
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