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Thermo Fisher Scientific VAV1 Monoclonal Antibody (GT557)
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Thermo Fisher Scientific VAV1 Monoclonal Antibody (GT557)

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VAV1 단백질을 인식하는 Mouse monoclonal antibody (Clone GT557). Western blot, IHC, ICC/IF 등 다양한 응용에 적합. Human 및 Mouse 반응성 확인됨. Protein G 정제, 1 mg/mL 농도의 액상 형태. 연구용으로만 사용 가능.

카탈로그번호
MA531488
판매단위
pk
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마지막 업데이트 2025. 08. 05. 오후 01:43
Thermo Fisher Scientific MA531488 VAV1 Monoclonal Antibody (GT557) 100 ul pk판매 단위 pk ·
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657,900원VAT 포함 723,690원

Thermo Fisher Scientific · Thermo Fisher Scientific VAV1 Monoclonal Antibody (GT557)

Applications and Tested Dilution

Application Tested Dilution Publications
Western Blot (WB) 1:500–1:3,000 -
Immunohistochemistry (IHC) - View 1 publication
Immunohistochemistry (Paraffin) (IHC (P)) 1:100–1:1,000 -
Immunocytochemistry (ICC/IF) 1:100–1:1,000 -

Product Specifications

항목 내용
Species Reactivity Human, Mouse
Published Species Not Applicable
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Clone GT557
Immunogen Recombinant protein encompassing a sequence within the center region of human VAV1
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Protein G
Storage Buffer PBS
Contains No preservative
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2787119

Product Specific Information

  • Keep as concentrated solution.
  • Predicted reactivity: Mouse (92%), Rat (92%), Pig (96%), Bovine (96%).
  • Positive Control: Jurkat, NCI-H929.
  • Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. It interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation, or vasoconstriction. Optineurin may also function in cellular morphogenesis, membrane trafficking, vesicle trafficking, and transcription activation through its interactions with RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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