Thermo Fisher Scientific SF3B2 Polyclonal Antibody
Thermo Fisher Scientific의 SF3B2 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 SF3B2 단백질 검출에 적합합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제된 고순도 제품입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human SF3B2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720617 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
SF3B2 is a subunit of the splicing factor SF3B required for A complex assembly, formed by stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence-independent binding of the SF3A/SF3B complex upstream of the branch site is essential and may anchor U2 snRNP to the pre-mRNA. It may also participate in E complex assembly and belongs to the minor U12-dependent spliceosome involved in splicing of rare nuclear pre-mRNA introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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