Thermo Fisher Scientific BMP-3 Polyclonal Antibody
BMP-3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 합성 펩타이드 면역원 기반, Affinity chromatography로 정제. PBS/glycerol buffer에 보관, -20°C 저장 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BMP3 (Accession P12645), corresponding to amino acid residues R286–K336. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818332 |
Product Specific Information
Antibody detects endogenous levels of total BMP3.
Target Information
The BMPs (Bone Morphogenetic Proteins) belong to the TGF-Beta superfamily. They stimulate the production of bone matrix proteins and influence stromal cell and osteoclast proliferation, key processes in bone marrow development.
In addition to promoting ectopic bone and cartilage formation, BMPs regulate growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal, epithelial, hematopoietic, and neuronal cells.
BMPs also play roles in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary, and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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