Thermo Fisher Scientific RACGAP1 Monoclonal Antibody (23A8)
RACGAP1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 23A8). Western blot, IHC, ICC, IP 등 다양한 응용에 적합. Protein G 정제, 1 mg/mL 농도, Human/Mouse/Rat 반응성. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2 µg/mL | View 2 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | 10 µg/mL | – |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
| Immunoprecipitation (IP) | 4 µg | – |
| Neutralization (Neu) | – | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 23A8 |
| Immunogen | Recombinant, full length, human RAC protein (RACGAP1, UniProt ID: Q9H0H5-1, antigen range: 1–632) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | TBS with 30% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_560813 |
Product Specific Information
- Recommended positive control: rat brain microsomal protein
- MA1-20580 detects a band of approximately 21 kDa
Target Information
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia, and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42, which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: MA1-20580_RACGAP1_Q9H0H5-1_House_mouse.svg, MA1-20580_RACGAP1_Q9H0H5-1_House_mouse_PDP.jpeg)
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