Thermo Fisher Scientific EMR4 Polyclonal Antibody
EMR4 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunocytochemistry에 사용 가능. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제. 1 mg/mL 농도의 액상 형태로 제공되며 4°C 또는 -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 108–164 of human EMR4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2553497 |
Product Specific Information
- Detects endogenous EMR4 protein with a molecular weight of approximately 51 kDa.
- Purity >95% confirmed by SDS-PAGE.
Target Information
FIRE (also known as EMR4) is a 689 amino acid protein encoded by the human EMR4 gene. It belongs to the G protein-coupled receptor 2 family (LN-TM7 subfamily).
The EGF-TM7 family proteins contain EGF-like domains at their extracellular N-terminus linked to a classical seven-transmembrane domain.
FIRE mediates interactions between myeloid and beta cells, functioning as a membrane-bound, multi-pass protein cleaved into two subunits: an extracellular alpha subunit and a seven-transmembrane subunit.
It contains one GPS (G protein-coupled receptor proteolytic cleavage site) domain and two EGF-like domains, the latter involved in ligand interaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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