Thermo Fisher Scientific UGT1A1 Polyclonal Antibody
UGT1A1 단백질을 인식하는 Thermo Fisher Scientific의 고트 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 trehalose로 안정화된 동결건조 형태. 인간 시료에 반응하며 연구용으로 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific UGT1A1 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human Glucuronosyltransferase 1A1 (UGT1A1), Leu60–Thr168 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609188 |
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules such as steroids, bilirubin, hormones, and drugs into water-soluble, excretable metabolites.
It is part of a complex locus including thirteen unique alternate first exons and four common exons. Four of the alternate exons are pseudogenes, while nine can be spliced to the common exons, producing proteins with distinct N-termini and identical C-termini.
Each first exon encodes the substrate binding site and has its own promoter. The preferred substrate is bilirubin, with moderate activity toward phenols, flavones, and C18 steroids.
Mutations in this gene cause Crigler-Najjar syndromes types I and II and Gilbert syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.