Thermo Fisher Scientific CD8 Monoclonal Antibody (fCD8), FITC
고양이 CD8 항원을 인식하는 Mouse IgG1 단클론 항체로 FITC 형광표지되어 있습니다. Flow Cytometry에 최적화되어 있으며, 498/517 nm 파장에서 효율적인 형광 검출이 가능합니다. PBS buffer에 0.1% sodium azide 포함, 4°C 암소 보관.
- 카탈로그번호
- MA528792
- 판매단위
- pk
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Thermo Fisher Scientific CD8 Monoclonal Antibody (fCD8), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 1 µg/10^6 cells
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | fCD8 |
| Immunogen | Feline thymocytes |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4 |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745751 |
Additional Formats
Target Information
Cluster of differentiation 8 (CD8) is a type I transmembrane glycoprotein of the immunoglobulin family that plays an integral role in T cell signal transduction, differentiation, and activation.
CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer (CD8α/CD8β) functioning as a co-receptor with TCR for MHC-I molecules.
It is also expressed on subsets of T cells, NK cells, monocytes, and dendritic cells as homodimers of CD8α.
Engagement of MHC-I/peptide complexes triggers Lck recruitment, leading to lymphokine production and cytotoxic T lymphocyte (CTL) activation, critical for pathogen and tumor cell clearance.
Differentiation of naive CD8+ T cells into CTLs is enhanced by IL-2, IL-12, and TGF-β1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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