Thermo Fisher Scientific GP130/CD130 Recombinant Rabbit Monoclonal Antibody (BLR114H)
GP130/CD130 단백질을 표적하는 Thermo Fisher의 재조합 토끼 단클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. HEK293F 발현 시스템 사용, 고순도 IgG 형식이며 1 mg/mL 농도로 제공됩니다. 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR114H |
| Immunogen | Recombinant protein representing the extracellular domain of Human GP130/CD130 (interleukin-6 receptor subunit beta, residues 23–323) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM).
This protein functions as part of the cytokine receptor complex, and its activation depends on cytokine binding to their receptors.
vIL6, encoded by the Kaposi sarcoma-associated herpesvirus, can bypass IL6R and directly activate this protein.
Knockout studies in mice indicate a critical role in regulating myocyte apoptosis.
Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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