Thermo Fisher Scientific HRH3 Polyclonal Antibody
HRH3 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC(P)에서 검증됨. 인간 및 마우스 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 뇌 신경전달물질 조절 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human histamine receptor H3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636133 |
Product Specific Information
This antibody detects endogenous levels of total Histamine 3 Receptor (HRH3) protein.
Target Information
H3 Histamine Receptor regulates the release of neurotransmitters such as norepinephrine and somatostatin.
In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in non-histamine-containing neurons, in both the central and peripheral nervous systems, it functions as a presynaptic heteroreceptor.
Multiple isoforms of H3 receptors are produced by alternative splicing. Histamine H3 receptor expression is primarily observed in the brain. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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