Thermo Fisher Scientific MGMT Monoclonal Antibody (OTI4D5), TrueMAB
인간 MGMT 단백질을 인식하는 Mouse monoclonal antibody. Western blot에 최적화된 고특이성 항체로, 1:2,000 희석 권장. 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D5 |
| Immunogen | Full length human recombinant protein of human MGMT produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
O6-Methylguanine-DNA Methyltransferase (MGMT) is an important DNA repair protein involved in tumor cell resistance to the cytostatic activity of chemotherapeutic alkylating agents. This protein protects normal cells from genotoxic and carcinogenic effects of DNA alkylation by removing alkyl groups from the O6 position of guanine. MGMT expression levels vary depending on cell type, tissue, species, and tumor characteristics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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