Thermo Fisher Scientific Phospho-DOK2 (Tyr139) Polyclonal Antibody
DOK2의 Tyr139 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 적합. Human 및 Mouse 시료 반응. 1 mg/mL 농도의 액상 제품으로 PBS/glycerol buffer에 보관. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DOK2 (Accession O60496), corresponding to amino acid residues around phosphorylated Tyr139 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903238 |
Product Specific Information
This antibody detects endogenous levels of DOK2 only when phosphorylated at Tyr139.
Target Information
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein associated with CML. This encoded protein binds p120 from CML cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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