Thermo Fisher Scientific PADI4 Polyclonal Antibody
Human PADI4 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, Western Blot 및 IHC(Paraffin) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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- PA582569
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- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PADI4 (Product #RP-88576). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789727 |
Product Specific Information
Immunogen sequence:
CEDDEVLDSE DLQDMSLMTL STKTPKDFFT NHTLVLHVAR SEMDKVRVFQ ATRGKLSSKC SVVLGPKWPS HYLMVPGGKH NMDFYVEALA FPDTDFPGLI TLTISLLD
Target Information
Catalyzes the citrullination/deimination of arginine residues of proteins.
Citrullinates histone H3 at Arg-8 and/or Arg-17 and histone H4 at Arg-3, which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription.
Citrullinates EP300/P300 at Arg-2142, which favors its interaction with NCOA2/GRIP1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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