Thermo Fisher Scientific LIPG Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LIPG. Recombinant protein control fragment (Product #RP-88732). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LIPG,uniProtId:Q9Y5X9-1,ncbiNodeId:9606,antigenRange:34-169,antigenLength:500,antigenImageFileName:PA5-82568_LIPG_Q9Y5X9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82568_LIPG_Q9Y5X9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789726

Product Specific Information

Immunogen sequence: KLHKPKATQT EVKPSVRFNL RTSKDPEHEG CYLSVGHSQP LEDCSFNMTA KTFFIIHGWT MSGIFENWLH KLVSALHTRE KDANVVVVDW LPLAHQLYTD AVNNTRVVGH SIARMLDWLQ EKDDFSLGNV HLIGYS

Target Information

LIPG (Lipase G, Endohelial type) is an endothelial lipase which is a novel member of the lipoprotein lipase gene family. LIPG is synthesized by endothelial cells and functions at the site of synthesis. LIPG most likely plays a physiological role in modulating lipoprotein metabolism. Overexpressed LIPG has been shown to reduce HDL cholesterol levels, whereas an LIPG deficiency appears to be effective in elevating HDL cholesterol levels in animals. LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. Also, LIPG is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. LIPG is a carboxyl esterase that hydrolyzes high density lipoproteins, emulsifies triglycerides, is essential for the efficient digestion of dietary fats and can bind to heparin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.