
Thermo Fisher Scientific ERAS/HRAS2 Polyclonal Antibody
ERAS/HRAS2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat에 반응하며, Protein A 정제 및 고순도 보장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ERAS/HRAS2, amino acids 20–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The human ERAS gene was initially reported as a processed pseudogene (HRasp, Ha-Ras2) with several base substitutions in coding regions, but later described as potentially encoding a functional human ERAS protein.
The ERAS oncogene supports tumorigenic growth of embryonic stem cells by producing a constitutively active Ras protein.
ERAS protein shares less than 50% amino acid identity with H-Ras, another member of the Ras family, but retains key conserved domains essential for Ras function.
It also contains amino acid residues identical to those found in active Ras mutants and induces oncogenic transformation in NIH 3T3 cells.
The human ERAS gene is localized in the chromosomal region Xp11.23.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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