Thermo Fisher Scientific CD1d1 Polyclonal Antibody
Thermo Fisher Scientific의 CD1d1 Polyclonal Antibody는 Mouse와 Rat 시료에 반응하며, WB, IHC, Flow Cytometry, ELISA 등 다양한 응용에 적합합니다. KLH 결합 합성 펩타이드(aa 165-270)를 면역원으로 사용한 Rabbit IgG 폴리클로날 항체로, 고순도 Protein A 정제 및 안정한 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse CD1d1, amino acids 165–270 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD1d is a heavy chain associated with beta-2 microglobulin on cortical thymocytes. Independent expression of CD1d has also been observed on human intestinal epithelial cells. CD1d is the sole group 2 member of the CD1 family of MHC-like glycoproteins. The CD1d gene encodes a divergent transmembrane glycoprotein structurally related to MHC proteins, forming heterodimers with beta-2-microglobulin. CD1 proteins present lipid and glycolipid antigens to T cells. The human genome contains five CD1 family genes on chromosome 1, differing in localization and ligand specificity. CD1d localizes to late endosomes and lysosomes via a tyrosine-based motif in its cytoplasmic tail. Diseases associated with CD1D include Mycobacterium Malmoense and autoimmune disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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