Thermo Fisher Scientific MRPL11 Polyclonal Antibody
Human MRPL11 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS 및 40% glycerol buffer에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific MRPL11 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPL11. Recombinant protein control fragment (Product #RP-100635). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644118 |
Product Specific Information
Immunogen sequence:
PTVSYFLKAA AGIEKGARQT GKEVAGLVTL KHVYEIARIK AQDEAFALQD VPLSSVVRSI IGSARSLGIR
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 91%
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and participate in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with an estimated 75% protein to rRNA composition, unlike prokaryotic ribosomes where the ratio is reversed. Mammalian mitoribosomes do not contain a 5S rRNA. The proteins comprising the mitoribosome differ greatly among species, making sequence homology recognition difficult. The MRPL11 gene encodes a 39S subunit protein, with three transcript variants encoding different isoforms. Pseudogenes are found on chromosomes 5q and 12q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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