Thermo Fisher Scientific alpha Adaptin Monoclonal Antibody (AP6), Alexa Fluor 555
Alexa Fluor 555로 표지된 alpha Adaptin 단클론 항체로, 다양한 포유류 시료에서 AP2 복합체를 검출 가능. 면역세포화학(ICC/IF)에 적합하며, 553/568 nm의 형광 특성을 가짐. 4°C 암조건 보관, 연구용으로만 사용.
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Thermo Fisher Scientific alpha Adaptin Monoclonal Antibody (AP6), Alexa Fluor 555
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AP6 |
| Immunogen | Purified adaptors |
| Conjugate | Alexa Fluor™ 555 |
| Excitation / Emission Max | 553 / 568 nm |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2722855 |
Additional Formats
Product Specific Information
MA1-064A555 detects assembly polypeptide 2 (AP2) from a wide variety of mammalian sources, including human, hamster, monkey, bovine, rat, and mouse.
It recognizes the products of both alpha-adaptin genes, alpha A and alpha C, as well as an alternatively spliced isoform of alpha adaptin found in neurons.
Target Information
Component of the adaptor protein complex 2 (AP-2).
Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways.
AP-2 is involved in clathrin-dependent endocytosis, facilitating cargo selection and vesicle formation.
It serves as a cargo receptor to selectively sort membrane proteins involved in receptor-mediated endocytosis and plays a role in recycling synaptic vesicle membranes.
The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane and acting as a scaffolding platform for endocytic accessory proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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