Thermo Fisher Scientific LSM11 Polyclonal Antibody
Thermo Fisher Scientific의 LSM11 폴리클로날 항체는 Human 및 Rat 시료에 반응하며 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 항체로, PBS와 글리세롤 버퍼에 보관됩니다. 세포 성장 및 RNA 처리 연구에 활용됩니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human LSM11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720968 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
LSm11 is a 360 amino acid protein localized in the nucleus and part of the LSm subfamily of snRNP Sm proteins. It contains an N-terminal domain essential for pre-mRNA cleavage and binds specifically to U7 snRNA, playing roles in cell cycle regulation and cell growth. The gene encoding LSm11 maps to human chromosome 5, which comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-77241_LSM11_P83369-1_Rabbit_PDP.jpeg)
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