Thermo Fisher Scientific STIM2 Polyclonal Antibody
STIM2 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 최적화된 연구용 항체로, 액상 형태이며 4°C에서 보관. 인간 STIM2의 600–650번 잔기 영역을 면역원으로 사용.
- 카탈로그번호
- A304429Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific STIM2 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 600–650 of Human Stromal Interaction Molecule 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
In T lymphocytes, the sole pathway for Ca²⁺ entry following antigen-receptor binding is through store-operated Ca²⁺-release-activated Ca²⁺ (CRAC) channels. These channels consist of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), which acts as a Ca²⁺ sensor and activates CRAC channels by migrating to the plasma membrane from ER-like Ca²⁺ stores.
A related molecule, STIM2, inhibits STIM1-mediated store-operated Ca²⁺ entry and can form complexes with STIM1, suggesting a coordinated role in Ca²⁺ regulation. At least three isoforms of STIM2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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