
Thermo Fisher Scientific CELSR1 Polyclonal Antibody
CELSR1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 1 mg/mL 액상 형태로 제공되며 4°C에서 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CELSR1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 2775 to 2825 of human Cadherin, EGF LAG Seven-Pass G-Type Receptor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
CELSR1 is a member of the flamingo subfamily, part of the cadherin superfamily.
The flamingo subfamily consists of nonclassic type cadherins that do not interact with catenins.
These cadherins are located at the plasma membrane and have:
- 9 cadherin domains
- 7 epidermal growth factor-like repeats
- 2 laminin A G-type repeats in their ectodomain
- 7 transmembrane domains, unique to this subfamily
CELSR1 is thought to function as a receptor involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and EGF-like domains contributing to cell adhesion and receptor-ligand interactions.
This gene is developmentally regulated and neural specific, playing a role in early embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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