Thermo Fisher Scientific PIWIL2 Polyclonal Antibody
Thermo Fisher Scientific의 PIWIL2 Polyclonal Antibody는 인간 및 랫트 시료에 반응하는 sheep 유래 IgG 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, 재구성 후 0.2 mg/mL 농도로 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human PIWIL2 (Lys216–Asp379) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606454 |
Product Specific Information
- In direct ELISAs, less than 4% cross-reactivity with recombinant human PIWIL4 is observed.
- Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
The piwi gene of Drosophila belongs to a novel class of evolutionarily conserved genes known as the piwi or Argonaute family. The Piwi family is essential for germ and stem cell development in invertebrates. Two Piwi members, MIWI and MILI (also known as Miwi-like, Piwil2, Piwi-like protein 2), are critical for spermatogenesis in mice.
MIWI and MILI associate with piwi-interacting RNAs (piRNAs), which are 26–31 nucleotides long—distinct from microRNAs (miRNAs, 21–23 nt) and short interfering RNAs (siRNAs).
Murine piRNA loci, which are developmentally regulated, suggest that MILI may interact with different piRNA populations during germ cell development, playing a vital role in meiotic prophase progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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