Thermo Fisher Scientific FOXA2 Recombinant Rabbit Monoclonal Antibody (9H5L7)
FOXA2 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody. Western blot, ICC/IF, ChIP 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며, lot 간 일관성이 우수. 인비트로 발현 시스템으로 생산되어 동물 유래 성분이 없음.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:250–1:500 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | View 4 publications |
| ChIP assay (ChIP) | 2–3 µg/1×10⁶ cells | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9H5L7 |
| Immunogen | Protein corresponding to Human FOXA2 (aa 236–451) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2576439 |
Product Specific Information
This antibody is predicted to react with Monkey, Horse, Cat, and Dog.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to large rabbit immune repertoire
Target Information
FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors act as transcriptional activators for liver-specific genes such as albumin and transthyretin and also interact with chromatin. In mice, similar family members regulate metabolism and differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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