Thermo Fisher Scientific SERCA1 ATPase Polyclonal Antibody
SERCA1 ATPase 단백질을 특이적으로 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human SERCA1 ATPase (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ATP-dependent calcium pumps are responsible for maintaining low cytoplasmic free calcium concentrations. These pumps, located in intracellular organelles, are encoded by a family of enzymes known as sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases.
- SERCA1: Expressed exclusively in type II (fast) skeletal muscle.
- SERCA2: Generates two isoforms through tissue-dependent processing — SERCA2a (in type I skeletal, cardiac, and smooth muscle) and SERCA2b (expressed in all cell types).
- SERCA3: Found in non-muscle cells and less well characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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