Thermo Fisher Scientific XPG Polyclonal Antibody
XPG 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간·마우스·랫트 시료에 반응합니다. 액상 형태로 제공되며 항원 친화 크로마토그래피로 정제되었습니다. DNA 손상 복구 연구 등 기초 생명과학 연구용으로 적합합니다.
- 카탈로그번호
- PA576039
- 판매단위
- pk
카탈로그
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human XPG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719767 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight. The XPG protein, part of the flap endonuclease 1 (FEN-1) family, is essential for DNA repair of UV-induced damages. Human XPG nuclease makes the 3′ incision during nucleotide excision repair of DNA and cleaves DNA bubble structures near junctions of unpaired and duplex regions. A 29-amino acid region (residues 981–1009) contains PCNA binding activity, and Arg992 is crucial for this interaction. Replication Protein A (RPA) binds directly to XPA and XPG proteins involved in excision repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-76039_XPG_P28715-1_Rabbit.svg / PA5-76039_XPG_P28715-1_Rabbit_PDP.jpeg)
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