Thermo Fisher Scientific NOX2 Polyclonal Antibody
NOX2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간, 마우스, 랫트에서 반응합니다. 고순도(>95%)로 연구용에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 2 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human gp91-phox |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719762 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Mox1 and the glycoprotein gp91-phox are essential components of the NADPH oxidase complex, which generates superoxide in phagocytes, neuroepithelial bodies, vascular smooth muscle cells, and endothelial cells. The complex includes membrane-bound flavocytochrome subunits (gp91-phox and p22-phox) and cytosolic proteins (p47-phox and p67-phox). The p22- and gp91-phox subunits also act as O₂ sensors initiating cellular signaling under hypoxic conditions. Mox1 and gp91 share identical C-terminal sequences but differ in expression: gp91-phox is expressed in eosinophils, neutrophils, monocytes, and B-lymphocytes, whereas Mox1 is mainly found in the colon, with lower levels in the uterus and prostate.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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