Thermo Fisher Scientific TAB3 Polyclonal Antibody
Human TAB3 단백질을 인식하는 Rabbit Polyclonal Antibody로, NF-κB 신호전달 및 자가포식 연구에 적합합니다. IHC(P)에서 1:50–1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TAB3. Recombinant protein control fragment (Product #RP-95454). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648177 |
Product Specific Information
Immunogen sequence:
QPKPPFSVNP VYITYTQPTG PSCTPSPSPR VIPNPTTVFK ITVGRATTEN LLNLVDQEER SAAPEPIQPI SVIPGSGGEK GSHKYQRSSS SGSDDYA
Ortholog sequence identity:
- Mouse: 98%
- Rat: 98%
Target Information
TAB3 functions in the NF-κB signal transduction pathway. It forms a ternary complex with TAK1 and TRAF2 or TRAF6 in response to TNF or IL-1 stimulation. TAK1 kinase activity activates NF-κB transcription factor. TAB2 and TAB3 interact with Beclin-1 in autophagy regulation; their overexpression inhibits autophagy, while depletion triggers it, indicating a control role in autophagy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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