Thermo Fisher Scientific GW182 Polyclonal Antibody
Rabbit 유래 GW182 폴리클로날 항체로 Western Blot 및 IHC에 적합. 인간, 마우스, 랫트 반응성. 합성 펩타이드 항원 사용, 비결합형 형태로 제공. 연구용으로 RNAi 및 microRNA 경로 관련 단백질 분석에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from human GW182 autoantigen conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity of this antibody: GW182.
Target Information
TNRC6A is a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. It associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies.
Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.
Publication Note: This RefSeq record includes a subset of the publications available for this gene. Please see the Entrez Gene record for additional references.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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