Thermo Fisher Scientific Human PALB2 Synthetic Peptide
Human PALB2 단백질의 C-말단 15개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-20796 항체의 블로킹 펩타이드로 사용 가능. BRCA1/2 관련 DNA 손상 복구 연구에 활용. 연구용으로만 사용.
- 카탈로그번호
- PEP0910
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human PALB2 Synthetic Peptide
Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human PALB2.
PEP-0910 can be used as a blocking peptide with polyclonal antibody PA5-20796.
Target Information
The breast cancer early onset proteins BRCA1 and BRCA2 are central to the repair of DNA damage by homologous recombination and are strongly associated with inherited breast and ovarian cancer.
The protein PALB2 is required for the localization of BRCA2 to sites of DNA damage and, like BRCA1 and BRCA2, is a breast cancer susceptibility gene.
PALB2 functions by directly binding to BRCA1, allowing the PALB2 protein to organize BRCA2 and the recombinase RAD51 at the site of DNA damage.
Analysis of the BRCA1–PALB2–BRCA2–RAD51 network may allow predictions of tumor responsiveness to therapeutic treatments.
At least four isoforms of PALB2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.