Thermo Fisher Scientific CD162 Monoclonal Antibody (TC2)
CD162(PSGL-1) 단백질을 인식하는 TC2 클론의 Mouse IgG1 단일클론 항체. 인간 시료에 반응하며, Flow Cytometry에 적합. 비결합형(Liquid, 1 mg/mL)으로 제공되며, 4°C 보관. 면역세포 표면 접착 및 이동 연구에 유용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1.5–2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TC2 |
| Immunogen | Human thymocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157471 |
Additional Formats
Product Specific Information
This antibody reacts with an extracellular epitope of CD162, a 220 kDa type I integral membrane protein expressed as a disulfide-linked homodimer (sialomucin family).
CD162 is present on most peripheral blood T lymphocytes, monocytes, and granulocytes; it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.
Target Information
CD162 (PSGL-1) is a 120 kDa homodimer protein found on the surface of leukocytes and platelets.
It binds CD62P (P-selectin), CD62L (L-selectin), and to a lesser extent CD62E (E-selectin).
These interactions are critical for leukocyte adhesion, rolling, and extravasation.
CD162 serves as an important immune marker of T cell exhaustion in chronic viral infections and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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