Thermo Fisher Scientific MUNC18 Polyclonal Antibody
MUNC18 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot, IHC, IP 등에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, -20°C에서 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 3 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | – |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | – |
| Immunoprecipitation (IP) | Assay-dependent | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Dog, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: V(58)EDINKRREPIPS(70) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325854 |
Product Specific Information
PA1-742 detects Munc-18 from human, rat, and mouse tissues.
It has been successfully used in Western blot, immunohistochemistry, and immunoprecipitation procedures.
By Western blot, this antibody detects an approximately 67 kDa protein representing Munc-18 from rat and mouse whole brain extract.
The immunizing peptide corresponds to amino acid residues 58–70 from human Munc-18.
This sequence is completely conserved among human, mouse, rat, bovine, and canine Munc-18.
The immunizing peptide (Cat. # PEP-067) is available for use in neutralization and control experiments.
Target Information
This gene encodes a syntaxin-binding protein that plays a role in neurotransmitter release via regulation of syntaxin, a transmembrane attachment protein receptor.
Mutations in this gene are associated with infantile epileptic encephalopathy-4.
Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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