Thermo Fisher Scientific AKAP13/AKAP-Lbc Polyclonal Antibody
AKAP13/AKAP-Lbc 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 Immunoprecipitation에 최적화. 액상 형태로 제공되며 4°C 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 2754 and 2804 of human A kinase (PRKA) anchor protein 13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which share the function of binding to the regulatory subunit of protein kinase A (PKA), confining the holoenzyme to discrete cellular locations.
This gene encodes a member of the AKAP family. Alternative splicing produces multiple isoforms containing C-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains.
The DH domain mediates guanine nucleotide exchange activation for the Rho/Rac family of small GTP-binding proteins, converting inactive GTPase to its active form.
The PH domain has multiple functions, allowing these isoforms to serve as scaffolding proteins coordinating Rho signaling, anchoring protein kinase A, and enhancing ligand-dependent activity of estrogen receptors α and β.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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