Thermo Fisher Scientific STAT2 Polyclonal Antibody
STAT2 단백질을 인식하는 토끼 폴리클로날 항체로, 마우스 시료에 반응합니다. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 보존제 없이 -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the carboxy terminus of mouse Stat2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10983891 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases and form homo- or heterodimers that translocate to the cell nucleus to act as transcription activators.
In response to interferon (IFN), STAT2 forms a complex with STAT1 and the IFN regulatory factor family protein p48 (ISGF3G), acting as a transactivator but lacking direct DNA-binding ability.
Transcription adaptor P300/CBP (EP300/CREBBP) interacts specifically with STAT2 and may be involved in blocking the IFN-alpha response by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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