Thermo Fisher Scientific Human LFG Synthetic Peptide
인간 LFG 단백질의 N-말단 16개 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-20311의 블로킹 펩타이드로 사용됩니다. Fas 수용체 매개 세포사멸 억제 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PEP0431
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human LFG.
PEP-0431 can be used as a blocking peptide with polyclonal antibody PA5-20311.
Target Information
LFG (Lifeguard), a seven transmembrane spanning protein, is a member of a family that inhibits apoptotic cell death induced by the Fas receptor. LFG is the human homolog of rat NMP35 and contains a conserved transmembrane domain and a small cytoplasmic domain. Studies have shown that LFG protects cells from Fas-mediated neuronal cell death in a unique manner. It binds to the Fas receptor but does not reduce Fas expression or interfere with FADD binding. LFG does not protect against TNF-alpha mediated cell death. Although ubiquitously expressed, Northern blot analysis shows increased expression in the hippocampus and other neural tissues, indicating a potential protective role in neurodegenerative diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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