Thermo Fisher Scientific Human ROS1, GST Tag Recombinant Protein

Thermo Fisher Scientific Human ROS1, GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution: Assay-dependent
Publications: -

Product Specifications

Product Specific Information

• For maximum recovery, spin prior to use.
• Aliquots of the 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
• For larger sizes, aliquots may be prepared to reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
• Never store kinase diluted.
• If properly stored at -80°C, product is guaranteed for 6 months from date of purchase.
• Protein Form: Cytoplasmic

Target Information

ROS1 is a tyrosine kinase that functions as a growth or differentiation factor receptor.
Protein kinases transfer a phosphate group from ATP to substrate proteins, mediating signal transduction in eukaryotic cells.
They regulate cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, movement, apoptosis, and differentiation.
The protein kinase family includes over 500 gene products and is classified into 8 major groups based on catalytic domain sequence comparison.
The tyrosine kinase (TK) group regulates cell-cell interactions such as differentiation, adhesion, motility, and death.
Approximately 90 TK genes are known—58 receptor TKs (e.g., EGFR, EPH, FGFR, PDGFR, TRK, VEGFR families) and 32 cytosolic TKs (e.g., ABL, FAK, JAK, SRC families).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.